The world is a complex system, and understanding it scientifically requires advanced computational resources and approaches. Engineers design the most powerful computers on Earth in order to model and simulate physical systems such as global climate, the expansion of the universe, and the behavior of matter at an atomic level. But today, high performance scientific computing means more than just supercomputers running numerical models, expanding to large-scale data analysis, AI and machine learning, visualization, and distributed and heterogeneous hardware systems.

UChicago CS researchers are changing the face of high performance computing (HPC), creating new computing paradigms at scale for understanding physical, biological, social, and ecological systems and answering the most significant questions facing society. Faculty lead efforts to apply the latest AI and data science approaches for scientific discovery, from computational imaging and spectroscopy to bioinformatics, neuroscience, and agriculture. In these areas, as well as in the development and application of new exascale systems such as Aurora, UChicago CS benefits from a strong partnership with Argonne National Laboratory.

Labs & Groups

Globus Labs

Ian Foster, Kyle Chard
Realizing a world in which all research data are reliably, rapidly, and securely accessible, discoverable, and usable.

Large-Scale Systems Group (LSSG)

Andrew A. Chien
Exploring critical systems research questions underlying sustainable, scalable large-scale systems, including cloud, high performance, edge, and mobile/IoT computing.

Chameleon

Kate Keahey, Haryadi Gunawi
A configurable experimental environment for large-scale edge to cloud research.

Center for Translational Data Science

Robert Grossman
A research center developing the discipline of translational data science and applying to advance biology, medicine, healthcare and environmental research.

Related Faculty

Kyle Chard

Research Associate Professor of Computer Science

Andrew A. Chien

William Eckhardt Distinguished Service Professor of Computer Science

Anshu Dubey

Senior Scientist, CASE Affiliate

Todd Dupont

Professor Emeritus of Computer Science, Mathematics, and the James Franck Institute

Ian Foster

Arthur Holly Compton Distinguished Service Professor of Computer Science

Robert Grossman

Frederick H. Rawson Distinguished Service Professor in Medicine, Computer Science

Rana Hanocka

Assistant Professor of Computer Science

Kate Keahey

Senior Scientist, CASE Affiliate

Gordon Kindlmann

Associate Professor of Computer Science

Rick Stevens

Professor of Computer Science

Rebecca Willett

Professor of Computer Science, Statistics

News & Events

In the News

Globus Receives Multiple Honors in 2024 HPCwire Readers’ and Editors’ Choice Awards

Nov 20, 2024
In the News

Argonne Team Breaks New Ground in AI-Driven Protein Design

Nov 15, 2024
UChicago CS News

DOE Awards Fred Chong and his National Research Team $7.5M to Develop a SMART Software Stack to Control Quantum Computer Noise

Nov 12, 2024
UChicago CS News

CS/LSSG Showcases Sustainability Research and Education

Nov 11, 2024
UChicago CS News

Ph.D. Student Jibang Wu Receives the Stigler Center Ph.D. Dissertation Award for His Work Modeling the Incentive Structures of Reward and Recommendation–Based Systems

Oct 24, 2024
UChicago CS News

Rebecca Willett Receives the SIAM Activity Group on Data Science Career Prize

Oct 23, 2024
UChicago CS News

UChicago CS Researchers Shine at UIST 2024 with Papers, Posters, Workshops and Demonstrations

Oct 10, 2024
UChicago CS News

UChicago Scientists Receive Grant to Expand Global Data Management Platform, Globus

Oct 03, 2024
UChicago CS News

UChicago Researchers Demonstrate the Quantifiable Uniqueness of Former President Donald Trump’s Language Use

Sep 30, 2024
UChicago CS News

Five UChicago CS students named to Siebel Scholars class of 2025

Sep 20, 2024
UChicago CS News

NSF and Simons Foundation launch $20 million National AI Research Institute in Astronomy

Sep 18, 2024
In the News

Data Ecology: A Socio-Technical Approach to Controlling Dataflows

Sep 18, 2024
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